Annual General Meeting of Probiodrug AG Election of New Supervisory Board members

HALLE/SAALE, Germany, 10 June, 2015 – Probiodrug AG (Euronext Amsterdam: PBD), a biopharmaceutical company developing novel therapeutic solutions to treat Alzheimer’s disease (AD), has the honour to announce the following Supervisory Board changes following its Annual General Meeting (AGM) held on 10 June 2015. The shareholders have elected Ms Charlotte Lohmann and Mr Kees Been as new members of the Supervisory Board.

Dr Erich Platzer, Dr Dinnies von der Osten, Dr Jörg Neermann and Dr Olivier Litzka were re-elected as Supervisory Board Members. In addition, all resolutions proposed by the Company’s Management and Supervisory Board were approved at the meeting including:

• Adoption of the annual financial statements and the management report of Probiodrug AG for the financial year 2014
• Ratification of the actions of the Executive and Supervisory Board members for financial year 2014
• Appointment of the statutory auditor for the annual financial statements for the financial year 2015
• Remuneration of the Supervisory Board
• Authorization to acquire treasury shares
• Authorization to issue option bonds and/or convertible bonds
• Resolution on the adjustment of the Stock Option Programme 2014

Dr Konrad Glund, Chief Executive Officer of Probiodrug AG said: “On behalf of the entire Company, I would like to thank Dr Hubert Birner and Prof Georg Frank for their invaluable contribution in establishing Probiodrug as a successful public biopharmaceutical company. We are also pleased to welcome Ms Charlotte Lohmann and Mr Kees Been to the Supervisory Board. They are two industry experts with a profound background in drug development and public markets respectively, and we look forward to working with them.”

89.3 % of the voting shares were represented at the 2015 Probiodrug AG AGM.

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For more information, please contact:

Probiodrug

Dr Konrad Glund, CEO

Email: contact@probiodrug.de

Hume Brophy

Mary Clark, Supriya Mathur, Hollie Vile

Tel: +44 (0) 203 440 5653

Email: probiodrug@humebrophy.com

Notes to Editors:

About Probiodrug AG

Headquartered in Halle, Germany, Probiodrug AG (Euronext Amsterdam: PBD) is a biopharmaceutical company focused on the development of new therapeutic products for the treatment of Alzheimer’s disease.

Founded in 1997, the company successfully developed a novel therapeutic concept for diabetes – the DP4 inhibitors – which provided the basis for a novel class of antidiabetics – the gliptins. Its core capabilities are based on its long-standing expertise in the elucidation of the structure and function of enzymes involved in the modification of proteins and peptides, which play a central role in pathological conditions.

Today Probiodrug’s aim is to become a leading company in the development of Alzheimer’s disease treatments and to thereby provide a better life for Alzheimer’s disease patients. It has identified a new therapeutic concept linked to disease initiation and progression. The development approaches are targeting pyroglutamate-Abeta (pGlu-Abeta) as a therapeutic strategy to fight Alzheimer’s disease. The Company has medical use and composition of matter patents related to the inhibition of Glutaminyl Cyclase (QC) and anti-pGlu-Abeta- specific monoclonal antibodies, providing it, in the Company’s view, with a leading position in this field of research. www.probiodrug.de

About Alzheimer’s disease

Alzheimer’s disease is a neurological disorder, which is the most common form of dementia, and ultimately leads to death. Because Alzheimer’s disease cannot be cured and is degenerative, the affected patients must increasingly rely on others for assistance. Today, 44 million people worldwide currently live with the condition and this number is expected to almost double by 2030 and to more than triple by 2050 to over 132 million. Alzheimer’s also has an estimated, global societal cost of over $600 billion (World Alzheimer Report 2014).

Forward Looking Statements

Information set forth in this press release contains forward-looking statements, which involve a number of risks and uncertainties. The forward-looking statements contained herein represent the judgment of Probiodrug AG as of the date of this press release. Such forward-looking statements are neither promises nor guarantees, but are subject to a variety of risks and uncertainties, many of which are beyond our control, and which could cause actual results to differ materially from those contemplated in these forward-looking statements. We expressly disclaim any obligation or undertaking to release publicly any updates or revisions to any such statements to reflect any change in our expectations or any change in events, conditions or circumstances on which any such statement is based.