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About Vivoryon

We are focused on developing innovative small molecule-based medicines for the treatment of inflammatory and fibrotic disorders of the kidney. Driven by our passion for ground-breaking science and innovation, we strive to improve patient outcomes by changing the course of severe diseases through modulating the activity and stability of pathologically relevant proteins. Our most advanced program, varoglutamstat, a proprietary, first-in-class orally available QPCT/L inhibitor, is being evaluated to treat diabetic kidney disease.

Strategic Partnering and Corporate Update

October 26, 2026

Vivoryon’s key strategic priority remains securing the funding necessary to advance varoglutamstat into a Phase 2b clinical study in patients with advanced diabetic kidney disease, with the aim of confirming the compelling data observed in the VIVIAD and VIVA-MIND studies.

The Company has made further progress in its strategic partnering efforts and is engaged in advanced negotiations with different parties towards securing a partnership for varoglutamstat in kidney disease.

In parallel, Vivoryon has implemented additional cost-saving measures aimed at preserving its financial resources while pursuing its strategic partnering activities. The Company will provide a further business update, including updated cash runway guidance, as part of its Q3 financial results in early November.

All ongoing negotiations and potential partnerships remain subject to the customary risks and uncertainties associated with such processes, and there can be no assurance that any transaction or investment will materialize.